"We got a lot of momentum and a lot of confidence, but it seems like we took a step backward tonight," Charlie Villanueva said. "We're all frustrated tonight, and some guys let their emotions get the best of them."
Indiana led by as many as 17 points in the first half, but Detroit pulled to 53-45 at the intermission.
The Pacers scored the first 11 points of the second half, including five from Granger and four from Murphy, to move the margin to 19.
"Good starts are very important and we had two of them," Granger said. "We built the big lead early, then after they cut it eight at halftime, we came right back out and built it up again. That demoralizes the other team."
Indiana held an 85-67 lead at quarter's end and led by as many as 23 in the fourth as the few fans left booed loudly.
"We just didn't play with any energy," Jerebko said. "You saw it. Boston and tonight were like night and day."
Prince (knee) played for just the 10th time this season, finishing with seven points in 24 minutes. "I've got to be careful to make it worse -- Rip came back from an injury and got hurt again, and I've been out twice now." Prince said that he expects his relationship to Kuester to be fine going forward. ... Ben Gordon (groin) and Will Bynum (ankle) continued to sit out for Detroit. ... Kwame Brown played after having sat out the last five games due to coach's decisions. ... Luther Head and Hamilton picked up technicals for trash-talking in the third quarter.