| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Russell Wilson |
1. Russell Wilson, QB | SEA | L 30-28 at ATL | 24 | 36 | 385 | 2 | 1 | 2 | 0 | 109.1 |
| 2. Tom Brady, QB | NE | W 41-28 vs. HOU | 25 | 40 | 344 | 3 | 0 | 1 | 0 | 115.0 | |
| 3. Matt Schaub, QB | HOU | L 41-28 at NE | 34 | 51 | 343 | 2 | 1 | 1 | 0 | 90.6 | |
| 4. Joe Flacco, QB | BAL | W 38-35 at DEN | 18 | 34 | 331 | 3 | 0 | 1 | 1 | 116.2 | |
| 5. Peyton Manning, QB | DEN | L 38-35 vs. BAL | 28 | 43 | 290 | 3 | 2 | 3 | 1 | 88.3 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Colin Kaepernick |
1. Colin Kaepernick, QB | SF | W 45-31 vs. GB | 16 | 181 | 11.3 | 2 | 56 | 0 | |
| 2. Ray Rice, RB | BAL | W 38-35 at DEN | 30 | 131 | 4.4 | 1 | 32 | 0 | ||
| 3. Frank Gore, RB | SF | W 45-31 vs. GB | 23 | 119 | 5.2 | 1 | 26 | 0 | ||
| 4. Michael Turner, RB | ATL | W 30-28 vs. SEA | 14 | 98 | 7.0 | 0 | 33 | 0 | ||
| 5. Arian Foster, RB | HOU | L 41-28 at NE | 22 | 90 | 4.1 | 1 | 21 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Zach Miller |
1. Zach Miller, TE | SEA | L 30-28 at ATL | 8 | 142 | 17.8 | 1 | 34 | 0 | |
| 2. Wes Welker, WR | NE | W 41-28 vs. HOU | 8 | 131 | 16.4 | 0 | 47 | 0 | ||
| 3. Michael Crabtree, WR | SF | W 45-31 vs. GB | 9 | 119 | 13.2 | 2 | 20 | 0 | ||
| 4. Golden Tate, WR | SEA | L 30-28 at ATL | 6 | 103 | 17.2 | 1 | 29 | 0 | ||
| 5. Torrey Smith, WR | BAL | W 38-35 at DEN | 3 | 98 | 32.7 | 2 | 59 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
Ray Lewis |
1. Ray Lewis, LB | BAL | W 38-35 at DEN | 10 | 7 | 17 | 0.0 | 0 | 0 | 0 |
| 2. Bradie James, LB | HOU | L 41-28 at NE | 2 | 9 | 11 | 0.0 | 0 | 0 | 0 | |
| 3. Terrell Suggs, LB | BAL | W 38-35 at DEN | 10 | 0 | 10 | 2.0 | 1 | 0 | 0 | |
| 4. Brad Jones, LB | GB | L 45-31 at SF | 9 | 1 | 10 | 0.0 | 0 | 0 | 0 | |
| 5. Aqib Talib, CB | NE | W 41-28 vs. HOU | 9 | 1 | 10 | 0.0 | 0 | 0 | 0 | |
